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mb49  (CancerTools Org)


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    CancerTools Org mb49
    Mb49, supplied by CancerTools Org, used in various techniques. Bioz Stars score: 99/100, based on 691 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mb49/product/CancerTools Org
    Average 99 stars, based on 691 article reviews
    mb49 - by Bioz Stars, 2026-06
    99/100 stars

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    mb49  (CancerTools Org)
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    mb49 cells  (Procell Inc)
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    Procell Inc mb49 cells
    Drug release and tumor-killing effects of MR@BCG. (A) The loading capacity and encapsulation efficiency of PTX under different coating concentrations. (B) The release of free PTX from MRs over time in urine and PBS. (C) The tumor-killing effects of MR and PTX on bladder cancer <t>MB49</t> cells. (D) Propidium iodide (PI) staining of MB49 cells treated with PBS, bare MRs, PTX, and MRs with PTX, respectively. Scale bar: 200 μm.(E to H) Expression of maturation markers of CD4 + , CD8 + , CD86 + , and CD206 + after 7 d of incubation with MR@BCG or control samples. (I to L) Concentrations of tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), interleukin-2 (IL-2), and interleukin-6 (IL-6) after incubation with MR@BCG or control samples for 48 h.
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    Drug release and tumor-killing effects of MR@BCG. (A) The loading capacity and encapsulation efficiency of PTX under different coating concentrations. (B) The release of free PTX from MRs over time in urine and PBS. (C) The tumor-killing effects of MR and PTX on bladder cancer MB49 cells. (D) Propidium iodide (PI) staining of MB49 cells treated with PBS, bare MRs, PTX, and MRs with PTX, respectively. Scale bar: 200 μm.(E to H) Expression of maturation markers of CD4 + , CD8 + , CD86 + , and CD206 + after 7 d of incubation with MR@BCG or control samples. (I to L) Concentrations of tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), interleukin-2 (IL-2), and interleukin-6 (IL-6) after incubation with MR@BCG or control samples for 48 h.

    Journal: Cyborg and Bionic Systems

    Article Title: Hybrid-Driven Bacillus Calmette–Guérin Carrier for Targeted Immuno-Chemo Combo Therapy in Bladder Cancer

    doi: 10.34133/cbsystems.0492

    Figure Lengend Snippet: Drug release and tumor-killing effects of MR@BCG. (A) The loading capacity and encapsulation efficiency of PTX under different coating concentrations. (B) The release of free PTX from MRs over time in urine and PBS. (C) The tumor-killing effects of MR and PTX on bladder cancer MB49 cells. (D) Propidium iodide (PI) staining of MB49 cells treated with PBS, bare MRs, PTX, and MRs with PTX, respectively. Scale bar: 200 μm.(E to H) Expression of maturation markers of CD4 + , CD8 + , CD86 + , and CD206 + after 7 d of incubation with MR@BCG or control samples. (I to L) Concentrations of tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), interleukin-2 (IL-2), and interleukin-6 (IL-6) after incubation with MR@BCG or control samples for 48 h.

    Article Snippet: MB49 cells were purchased from Procell.

    Techniques: Encapsulation, Staining, Expressing, Incubation, Control

    In vivo therapeutic efficacy of MR@BCG against bladder cancer. (A) Schematic of the study protocol in establishing orthotopic MB49 bladder tumors in C57BL/6 mice, followed by various intravesical administrations. (B) Representative in vivo bioluminescence images and (C) bioluminescence intensity of MB49-tumor-bearing mice under various intravesical administrations over the treatment course. (D) Survival rate and (E) body weight of mice under various intravesical administrations over the treatment course. (F to I) Concentrations of TNF-α, IFN-γ, IL-2, and IL-6 in bladder tissues after treatment with MR@BCG or control samples. (J) Immunofluorescence images showing CD8 + and CD86 + cells. Scale bar: 70 μm (K) Hematoxylin and eosin (H&E) staining images of bladder tissue. Scale bar: 125 μm. DAPI, 4′,6-diamidino-2-phenylindole.

    Journal: Cyborg and Bionic Systems

    Article Title: Hybrid-Driven Bacillus Calmette–Guérin Carrier for Targeted Immuno-Chemo Combo Therapy in Bladder Cancer

    doi: 10.34133/cbsystems.0492

    Figure Lengend Snippet: In vivo therapeutic efficacy of MR@BCG against bladder cancer. (A) Schematic of the study protocol in establishing orthotopic MB49 bladder tumors in C57BL/6 mice, followed by various intravesical administrations. (B) Representative in vivo bioluminescence images and (C) bioluminescence intensity of MB49-tumor-bearing mice under various intravesical administrations over the treatment course. (D) Survival rate and (E) body weight of mice under various intravesical administrations over the treatment course. (F to I) Concentrations of TNF-α, IFN-γ, IL-2, and IL-6 in bladder tissues after treatment with MR@BCG or control samples. (J) Immunofluorescence images showing CD8 + and CD86 + cells. Scale bar: 70 μm (K) Hematoxylin and eosin (H&E) staining images of bladder tissue. Scale bar: 125 μm. DAPI, 4′,6-diamidino-2-phenylindole.

    Article Snippet: MB49 cells were purchased from Procell.

    Techniques: In Vivo, Drug discovery, Control, Immunofluorescence, Staining